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MRGPRX4 modulator-2

CAS No. 2492595-24-9

MRGPRX4 modulator-2( —— )

Catalog No. M35523 CAS No. 2492595-24-9

MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MRGPRX4 modulator-2
  • Note
    Research use only, not for human use.
  • Brief Description
    MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM.
  • Description
    MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MRGPR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2492595-24-9
  • Formula Weight
    348.68
  • Molecular Formula
    C15H9ClF4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (143.40 mM; Ultrasonic (<60°C)
  • SMILES
    O=C(O)C1=CC=CC(=C1F)COC2=CC=C(C=C2Cl)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)
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